by Elizabeth Swanberg | Jan 8, 2019 | FAQs
You can export the sequences generated in Design by downloading the structures’ PDBs or FASTAs. Begin by opening the file containing your Design results. As shown below you will be able to select the structures you would like to download data for by checking the...
by Elizabeth Swanberg | Jan 8, 2019 | FAQs
The number of repeats and the unique combination of Actions you should run when making mutations to your protein will depend on two factors. First, how large will your following experimental tests be; how many sequences are you looking to generate? Second, what level...
by Elizabeth Swanberg | Jan 8, 2019 | FAQs
Cyrus Bench Loop Rebuild is currently in Beta testing. However, the method proposed is great and routinely used to do loop extensions. Here is a suggested workflow. 1.) Insert desired loop sequences into your FASTA sequence, then run in Homology Modeling as a...
by Elizabeth Swanberg | Jan 8, 2019 | FAQs
When looking for stabilizing mutations it is helpful to compare DDG results across different models. The standard deviation is normally 1-2 between models, so a DDG of less than -1 would be interesting to look at. For more information on how to run DDG and interpret...
by Elizabeth Swanberg | Jan 8, 2019 | FAQs
Yes, we plan on there eventually being a command-line interface for CAD. It will not expose the user to direct interaction with Rosetta, but will expand the power of existing CAD...
