by Elizabeth Swanberg | Jan 20, 2019 | Antibodies, Workflows
BACKGROUND B Cells can have surface antibodies that can bind proteins. This can elicit an immune response if other factors are present to activate the B Cell. One way to inhibit or increase antibody binding to a protein is to alter its surface residues to change the...
by Elizabeth Swanberg | Jan 20, 2019 | Antibodies, Workflows
Click Here to Download This Article as a PDF INTRODUCTION The overarching goal of this workflow is to show Bench users how they may use their understanding of a complex protein-protein interface to generate specificity variants on that sequence, yielding orthogonal...