by Elizabeth Swanberg | Dec 31, 2018 | Analysis, Tools
BACKGROUND Immunogenicity is the propensity of a molecule to provoke a response by the immune system. In many cases this is the desired behavior of the immune system, recognizing foreign objects and targeting them for neutralization or removal. However immunogenicity...
by Elizabeth Swanberg | Dec 31, 2018 | Analysis, Tools
Delta Delta G (DDG) is a metric for predicting how a single point mutation will affect protein stability. DDG, often referred to as 𝚫𝚫G, is the change in the change in Gibbs free energy (double changes intended). DDG is a measure of the change in energy between the...
