by Elizabeth Swanberg | Jan 20, 2019 | Advanced use of Design, Workflows
Workflows for rescoring protein-protein complex from other software, and disulfide bond removal with maintained overall...
by Elizabeth Swanberg | Jan 20, 2019 | Antibodies, Workflows
BACKGROUND B Cells can have surface antibodies that can bind proteins. This can elicit an immune response if other factors are present to activate the B Cell. One way to inhibit or increase antibody binding to a protein is to alter its surface residues to change the...
by Elizabeth Swanberg | Jan 20, 2019 | Introductory Workflows, Workflows
INTERFACE DDG WORKFLOW The free energy of an interface single point mutation (change in binding free energy) can be calculated using this workflow. Here we will look at mutations on the alpha-helical peptide BHRF1 in complex with the Bim BH3 domain, 2WH6. STEP BY...
